we do it!
Poli4Life is an innovative Start-up that deals with the extraction of Polyphenols from the waters resulting from olive oil production (AVO). In other words, from a waste (otherwise destined for disposal) we generate our product, a polyphenolic concentrate that we call Poli4Liquid.
Through an exclusive process - much cheaper than all the existing others - we transform what is “useless” into something precious plus… water.
And all this creating only 0.8% of final waste.
Poli4Life is a company strongly anchored to the territory: we are in Umbria, a region with a great olive-growing vocation, and from our areas we take our raw material (the AVO) which travel only a few kilometres to reach our storage silos.
They are characterized by the presence of multiple associated phenolic groups in more or less complex structures - generally of high molecular weight. The number and characteristics of such phenolic structures underline the unique physical, chemical, and biological properties of particular members of the polyphenol class.
Polyphenols are natural antioxidants present in plants (polyphenolic molecules such as flavonoids known as procyanidins, proanthocyanins, leucoanthocyanidins, piconogenols, tannins, etc.). They are useful in preventing the oxidation of lipoproteins and in reacting with free radicals, eliminating them.
Positive biomedical effects have been reported at cardiovascular level, against diseases related to senescence and skin pathologies. Polyphenols have such a positive effect on human health, that they are sometimes referred to as "vitamin P" in some texts. Many scientific publications confirm the healthy abilities of polyphenols.
The concentration of polyphenols in olive oil waters (AVO), from which Poli4Liquid derives, is higher than in olive oil; this is because the molecules under examination are hydrophilic and non-lipophilic. In addition, although hydroxytyrosol is the best-known polyphenol in Poli4Liquid, other Polyphenols are also present and all contribute to the improvement of human health. In fact, polyphenols not only have anti-radical and anti-inflammatory activity but also influence blood circulation, absorption of fats and cholesterol, reduce bacteria and increase cell defences.
Aging is a very complex process, characterized by a series of successive events that undermine the normal activity of organs, tissues and systems.
The peculiarity of this process is the 360-degree involvement of the whole organism with functional and structural variations that start from microscopic molecules such as proteins, nucleic acids and lipids and that propagate exponentially to the entire cell, tissue, organ, to the apparatus and finally to the human organism in its entirety
For this reason, it becomes important to understand the molecular mechanisms underlying these phenomena and to implement the appropriate remedies.
Among the mechanisms currently most accredited are:
Of great importance in the prevention of senescence and its complications is the safeguarding of nervous function.
In this context, polyphenols, on the one hand thanks to the ability to chelate metal ions, on the other hand through the ability to neutralize reactive oxygen species, have proved effective, especially in experimental models, in delaying the neurological damage present in example in chronic neurodegenerative diseases such as Alzheimer's and Parkinson's.
However, in addition to the scavenger action, the polyphenols seem to activate specific proteins, such as SIRT1 or sirtuins, involved in cellular protection and longevity, thus highlighting a particularly complex modulatory role.
The activity described above would also result in maintaining proper tissue oxygenation, and therefore in safeguarding the functionality of different organs and tissues. Photo protective and cosmetological activity.
The impressive antioxidant activity of these compounds has inevitably extended the potential applications of use of polyphenols from anti-aging medicine to cosmetology.
There are several studies in the literature in which this heterogeneous group of molecules has proved useful in:
These biological characteristics have thus allowed the polyphenols to enter fully among the anti-aging molecules, so much so that they are included in the formulation of both oral supplements and products for topical use.
The base concentrate (C1) represents the semi-finished product from which the Poli4Liquid is then produced. Characterized by a density slightly higher than water and a very high percentage of total polyphenols, C1 is suitable for those processes that require spraying the product, which would be very problematic using Poli4Liquid, given its density.
C1 is a somewhat perishable product so it is to be used within 2-3 months of production.
Il C1 è un prodotto alquanto deperibile per cui è da utilizzare nell’arco di 2-3 mesi dalla produzione.
The Polyphenols they are precious molecules, which can be used in different contexts: from cosmetics to nutraceuticals, from human and animal nutrition to the creation of compostable biopolymers. Poli4Life carries out constant research to experiment with their use in these fields, and to find new ones.